Season 3

For millennia, humans have believed that aging is inevitable. Yet thirty years ago, the work of Professor Cynthia Kenyon and her colleagues showed that a single gene mutation in a worm doubled its lifespan and postponed the diseases of aging. Recent work on the naked mole rat, a mammal like us, has…

What is a thought? Some may think that question is quite abstract, but it has huge implications for science and computer design.

Psychiatry is changing and will be unrecognizable in the next 10-20 years, given our new understanding about the role of brain circuits in the generation of emotions and behavior. This week we talk to Professor Karl Deisseroth, D.H. Chen Professor of Bioengineering and of Psychiatry and Behavioral …

This week we speak with Professor David Baker about the enormous scope for making new proteins and how that translates into practical uses to tackle diseases, such as Covid-19.

In the last 20 years or so, many new cancer treatments have emerged that provide greater precision and targeting of cancer cells. Today, we have a better understanding of the genetic components of cancer. Through novel technology and cutting-edge science, we’re now able to understand how the …

Genome editing holds the potential to be a transformative new therapy, and the pace of progress is truly breathtaking.

In this episode we explore the vastness of the dark genome and why "junk DNA" has been overlooked for so many decades.