Episodes

Theory and Practice explores the cutting edge of biology and computer science through conversations with leaders in the field. This week, your hosts Alex and Anthony introduce themselves and discuss the origins of the show.

In this episode, Princeton University’s Barbara Englehardt reveals what she’s working on in epigenetics and exploratory data analysis, and examines the theoretical foundations for machine learning and how they are applied in practice. Barbara is currently on leave from Princeton University and is a principal scientist at Genomics Plc.

Jessica Mega, Chief Medical Officer at Verily, discusses her career path, the intersection of data science and healthcare, and how medical tools can augment positive health outcomes.

Former Google CEO Eric Schmidt talks about the foundations of computer science, reflects on the role of data in healthcare, and discusses his views on the intersection of technology and life sciences as the next frontier.

In this episode, Sir Peter Donnelly, CEO of Genomics Plc and Professor of Statistical Science at the University of Oxford, explores the relationship between genetic variation and complex human diseases and talks about his career at the intersection of statistics and genetics.

Greg Corrado, senior research scientist with Google AI, examines the impact of artificial intelligence and machine learning on medicine and delves into the future of biological neuroscience.

Eric Lander, president and founding director of the Broad Institute of MIT and Harvard, joins the show to discuss human genetics and computational biology.

David Sontag, Associate Professor of Electrical Engineering and Computer Science at MIT, explores how artificial intelligence can transform medicine, and discusses the importance of fairness in machine learning.

Professor Daphne Koller is the CEO and founder of insitro. She joins the podcast to discuss how machine learning and biology can advance drug discovery and patient care.

Cori Bargmann is the head of science at the Chan Zuckerberg Initiative. She is also the head of the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior and the Torsten N. Wiesel Professor at The Rockefeller University in New York. She joins the podcast to discuss advancing science on a larger scale.

Zach Weinberg is the co-founder, president, and COO of Flatiron Health. He discusses his entrepreneurial journey and Flatiron Health's approach to accelerating cancer care and improving patient outcomes.

The hosts interview a panel of distinguished guests, including life sciences entrepreneur and investor Alexis Borisy, Finale Doshi-Velez of Harvard University's John A. Paulson School of Engineering and Applied Sciences, and Pardis Sabeti of the Broad Institute of MIT and Harvard.

One week until Theory and Practice returns! Join Anthony and Alex as they discuss cutting-edge health developments with leaders in biology and computer science.

Dr. Anne Carpenter is the inventor of CellProfiler and designed a method for coloring and analyzing cells. She works at the Broad Institute as the Senior Director of the Imaging Platform and is an Institute Scientist.

Theory and Practice speaks with Professor Sir Rory Collins, Head of Nuffield Department of Population Health at Oxford University and BHF (British Heart Foundation) Professor of Medicine and Epidemiology. Professor Collins is also Principal Investigator and Chief Executive of the UK Biobank.

Theory and Practice speaks with Professor Jennifer Listgarten, Professor in UC Berkeley's Electrical Engineering and Computer Sciences Department (EECS department) and the Center for Computational Biology, and Chan Zuckerberg investigator.

Theory and Practice speaks with Dr. Caroline Uhler, currently the Henry L. and Grace Doherty associate professor in EECS (Electrical Engineering & Computer Science) and IDSS (Institute for Data, Systems and Society) at MIT, and associate member of the Broad Institute where she is co-director of the Eric and Wendy Schmidt Center.

Dr. Krishna Yeshwant is Managing Partner at GV, and a practicing physician at Brigham and Women’s Hospital in Boston.

Dr. Timothy Yu walks us through his experience running the first "N of 1" drug trial for a young patient with a devastating genetic mutation.

David Altshuler is Executive Vice President, Global Research and Chief Scientific Officer at Vertex Pharmaceuticals.

Dr. Amy Abernethy is an oncologist, specialist in palliative care medicine, researcher, previous Professor of Medicine at Duke University School of Medicine, previous Scientific and Medical Chief Officer of Flatiron Health, and previous Principal Deputy Commissioner of the FDA.

Aviv Regev is a computational biologist and Executive Vice President of Genentech Research and Early Development. She was professor at the Broad Institute of MIT and Harvard and at the Department of Biology of the Massachusetts Institute of Technology, as well as investigator at the Howard Hughes Medical Institute.

Julia Vitarello is the mother of Mila Makovec, and the Founder and CEO of Mila’s Miracle Foundation.

In this episode we explore the vastness of the dark genome and why "junk DNA" has been overlooked for so many decades.