Episodes

In this episode we explore the vastness of the dark genome and why "junk DNA" has been overlooked for so many decades.

Genome editing holds the potential to be a transformative new therapy, and the pace of progress is truly breathtaking.

In the last 20 years or so, many new cancer treatments have emerged that provide greater precision and targeting of cancer cells.Today, we have a better understanding of the genetic components of cancer.Through novel technology and cutting-edge science, we’re now able to understand how the accumulation of molecular alterations in the genome leads to the coding of proteins that can promote uncontrolled cell division.New treatments are emerging at the genetic and molecular level, along with novel approaches to targeting the new microenvironment that cancers create.On this episode of Theory and Practice, we explore the future of cancer medicine, and there’s no better leader to turn to for that discussion than Dr. Jay Bradner. Since 2016, he’s been president of the Novartis Institutes for BioMedical Research, where he leads the discovery and development of life-changing therapies to benefit patients.Theory and Practice is a presentation of GV and Google AI.Th…

This week we speak with Professor David Baker about the enormous scope for making new proteins and how that translates into practical uses to tackle diseases, such as Covid-19.

Psychiatry is changing and will be unrecognizable in the next 10-20 years, given our new understanding about the role of brain circuits in the generation of emotions and behavior. This week we talk to Professor Karl Deisseroth, D.H. Chen Professor of Bioengineering and of Psychiatry and Behavioral Sciences at Stanford University and the Howard Hughes Medical Institute.

What is a thought? Some may think that question is quite abstract, but it has huge implications for science and computer design.

For millennia, humans have believed that aging is inevitable. Yet thirty years ago, the work of Professor Cynthia Kenyon and her colleagues showed that a single gene mutation in a worm doubled its lifespan and postponed the diseases of aging. Recent work on the naked mole rat, a mammal like us, has shown that risk of death need not increase with age.In the final episode of this season of Theory and Practice, we explore the genetic, cellular, and molecular basis of aging with Professor Kenyon and ask what harnessing this knowledge means for the future of healthcare.Theory and Practice is a presentation of GV and Google AI.This season we'll dive deep into the languages of life through explorations of the "dark genome", genome editing, protein folding, the future of aging, and more.Hosted by Anthony Philippakis (Venture Partner at GV) and Alex Wiltschko (Staff Research Scientist with Google AI), Theory and Practice opens the doors to the cutting edge of biology and …